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Research Overview

Stephanie Jo Brewster is a board-certified and licensed genetic counselor with over 20 years of clinical research experience. She has a longstanding interest in the ethical issues surrounding genetic and translational research and its impact on participating families. In her current and previous positions, Ms. Brewster has implemented and overseen numerous pediatric studies and clinical trials providing guidance around protocol and consent form development, IRB facilitation, infrastructure creation and study staff supervision. She has acted as a consultant to biotech companies conducting clinical research and has served on numerous committees of the National Society of Genetic Counselors. Ms. Brewster is a current member of the Boston Children's Institutional Review Board and previously served as a member of the Human Research Committee for Massachusetts General Hospital/Partners. Ms. Brewster is also a member of the Developmental Medicine-Clinical Research Laboratories (DM-CRL) Operations Team.
 

Research Background

Ms. Brewster received her Bachelor of Science degree in Biology from Syracuse University and her Master of Science degree in Human Genetics from Sarah Lawrence College. Ms. Brewster is board certified by the American Board of Genetic Counseling and licensed by the Massachusetts Genetic Counseling Board of Registration.

Selected Publications

  1. Bridgemohan C, Cochran DM, Howe YJ, Pawlowski K, Zimmerman AW, Anderson GM, Choueiri R, Sices L, Miller KJ, Ultmann M, Helt J, Forbes PW, Farfel L, Brewster SJ, Frazier JA and Neumeyer AM on behalf of the Autism Consortium Biomarkers Study Clinicians. Investigating Potential Biomarkers in Autism Spectrum Disorder. Front. Integr. Neurosci. 13 (31):1-11, 2019.
  2. Sices L, Pawlowski K, Farfel L, Phillips D, Howe Y, Cochran DM, Choueiri R, Forbes PW, Brewster SJ, Frazier JA, Neumeyer A, Bridgemohan C. Feasibility of Conducting Autism Biomarker Research in the Clinical Setting. J Dev Behav Pediatr. 38(7):483-492, 2017.
  3. Brewster SJ, Jacobsen C, Shen Y and Holm IA, “Genetic Testing and Counseling”, in Thakker RV, Whyte MP, Eisman JA and Igarashi T, Eds., Genetics of Bone Biology and Skeletal Disease (Elsevier Inc., 2017, 2nd Edition), pp. 159-169.
  4. Doyle DL, Awwad RI, Austin JC, Baty BJ, Bergner AL, Brewster SJ, Erby LA, Franklin CR, Greb AE, Grubs RE, Hooker GW, Noblin SJ, Ormond KE, Palmer CG, Petty EM, Singletary CN, Thomas MJ, Toriello H, Walton CS, and Uhlmann WR. Review and Update of the Genetic Counseling Practice Based Competencies by a Task Force of the Accreditation Council for Genetic Counseling. Journal of Genetic Counseling. 25(5):868-79, 2016.
  5. Field T, Brewster SJ, Towne M, and Campion MW. Emerging Genetic Counselor Roles within the Biotechnology and Pharmaceutical Industries: as Industry Interest Grows in Rare Genetic Disorders, How are Genetic Counselors Joining the Discussion?. Journal of Genetic Counseling. 25(4):708-19, 2016.
  6. Schully SD, Lam TK, Dotson WD, Chang CQ, Aronson N, Birkeland ML, Brewster SJ, Boccia S, Buchanan AH, Calonge N, Calzone K, Djulbegovic B, Goddard KAB, Klein RD, Klein TE, Lau J, Long R, Lyman GH, Morgan RL, Palmer CGS, Relling MV, Rubinstein WS, Swen JJ, Terry SF, Williams MS, and Khoury MJ. Evidence synthesis and guideline development in genomic medicine: current status and future prospects. Genetics in Medicine. 17(1):63-7, 2015.
  7. Holm IA, Savage SK, Green RC, Juengst E, McGuire A, Kornetsky S, Brewster SJ, Joffe S and Taylor P. Guidelines for return of research results from pediatric genomic studies: deliberations of the Boston Children’s Hospital Gene Partnership Informed Cohort Oversight Board. Genetics in Medicine. 16: 547-552, 2014.
  8. Kong SW, Shimizu-Motohashi Y, Campbell MG, Lee IH, Collins CD, Brewster SJ, Holm IA, Rappaport L, Kohane IS and Kunkel LM. Peripheral blood gene expression signature differentiates children with autism from unaffected siblings. Neurogenetics. 14(2):143-52, 2013.
  9. Kong SW, Collins CD, Shimizu-Motohashi Y, Holm IA, Campbell MG, Lee IH, Brewster SJ, Hanson E, Harris HK, Lowe KR, Saada A, Mora A, Madison K, Hundley R, Egan J, McCarthy J, Eran A, Galdzicki M, Rappaport L, Kunkel LM, and Kohane IS. Characteristics and Predictive Value of Blood Transcriptome Signature in Males with Autism Spectrum Disorders. PLoS ONE. 7(12): e49475, 2012.
  10. Shen Y, Dies KA, Holm IA, Bridgemohan C, Sobeih M, Caronna EB, Miller KJ, Frazier JA, Silverstein I, Picker J, Weissman L, Raffalli P, Jeste S, Demmer LA, Peters HK, Brewster SJ, Kowalczyk SJ, Rosen-Sheidley B, McGowan C, Duda AW, Lincoln SA, Lowe KR, Schonwald A, Robbins M, Hisama F, Wolff R, Becker R, Nasir R, Urion DK, Milunsky JM, Rappaport L, Gusella JF,Walsh CA, Wu BL, Miller DT and on behalf of the Autism Consortium Clinical Genetics/DNA Diagnostics Collaboration. Clinical Genetic Testing for Patients with Autism Spectrum Disorders. Pediatrics. 125(4): 727-735, 2010.