Kaifu Chen

Kaifu Chen leads a bioinformatics lab that develops methods to investigate genetic and epigenetic mechanisms for cell identity regulation. A key discovery in the lab is that cell identity genes are different from other genes such as housekeeping genes in the epigenetic mechanism to regulate their expression and mutations. The finding builds a knowledge foundation to develop technique for discovery of cell identity regulators, and further provides insights into cell identity regulation in development and diseases.