Researcher | Research Overview
The Moffitt laboratory is passionate about creating the next generation of image-based approaches to single-cell 'omics and leveraging these approaches to ask questions at the interface between commensal microbial communities and their host.
Researcher
Researcher | Research Background
Dr. Moffitt received his PhD in Physics from the University of California Berkeley where he built methods to follow the Angstrom-scale movements of individual enzymes in real time. He trained as a postdoctoral fellow at Harvard University where he co-developed a leading method for massively multiplexed single-molecule RNA imaging known as MERFISH.
Selected Publications
- Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling. https://www.biorxiv.org/content/10.1101/2023.05.08.539701v1
- Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain. https://www.nature.com/articles/s41593-023-01455-9
- Spatial and temporal profiling of the complement system uncovered novel functions of the alternative complement pathway in brain development. https://www.biorxiv.org/content/10.1101/2023.11.22.568325v1
- 4. The emerging landscape of spatial profiling technologies. https://www.nature.com/articles/s41576-022-00515-3