Rotation Projects | Overview
Project One
Endothelial-pericyte interactions in infantile hemangioma - role of ANGP1
Project Two
Defective Galpha-q signaling in human endothelial cells - capillary malformations in Sturge-Weber syndrome
Project Three
Valve endothelial cell contributions to fibrosis in the mitral valve - potential for mitral valve endothelial cells to differentiate into fibrotic cells via CD45 phosphatase.
Cardiac valve endothelial cells undergo endothelial to mesenchymal transformation (EndMT) in response to TGF-β (middle and right panels). Cells are stained for endothelial marker CD31 (red) and α-smooth muscle actin (green).